Illustration of Oregon Regenerative Medicine's equipment, location and ability to offer image-guided knee pain treatment without surgery

Knee pain can make everyday life harder. Walking upstairs, exercising, gardening, or even getting out of a chair may become uncomfortable when the knee joint is inflamed, unstable, or worn down. At Oregon Regenerative Medicine, chronic knee pain and knee osteoarthritis are among the most common conditions we treat with non-surgical regenerative options.

For many patients, the goal is simple: reduce pain, improve function, and delay or avoid more invasive procedures when appropriate. Rather than treating surgery as the first step, our doctors evaluate the cause of your knee pain and recommend a plan designed to support non-surgical healing, joint stability, and better movement.

Non-Surgical Knee Pain Treatment Options

Oregon Regenerative Medicine offers several regenerative medicine treatments for knee pain. These therapies rely on precise diagnosis and image guidance and are tailored to each patient’s diagnosis, imaging results, and goals.

PRP Therapy for Knee Pain

Platelet-rich plasma, or PRP, uses a concentrated sample of platelets from your own blood. Platelets contain growth factors that help calm inflammation and support tissue repair. During PRP therapy, this concentrated solution is injected into the knee joint or surrounding injured tissue. PRP may be recommended for knee osteoarthritis, chronic tendon irritation, or soft tissue injuries that have not improved with rest, physical therapy, or other conservative care.

Adipose-Derived Stem Cell Grafts for Knee Osteoarthritis

Adipose-derived stem cell grafts use a small sample of your own fat tissue, which contains regenerative cells and signaling factors. After processing, the graft is injected into the knee to help support the body’s natural repair response. This option may be considered for some patients with knee osteoarthritis or cartilage-related wear and tear, depending on the severity of joint damage and the patient’s overall health.

Prolotherapy for Knee Instability

Sometimes knee pain is linked to ligament laxity or joint instability, especially after an old injury. Prolotherapy uses targeted dextrose injections to stimulate a healing response in weakened ligaments or tendons. By strengthening support around the knee, prolotherapy may help reduce pain caused by looseness or poor joint mechanics.

What Knee Conditions Can Regenerative Medicine Treat?

Non-surgical knee treatments may be used for a variety of common knee problems, including mild to severe knee osteoarthritis, meniscus tears, chronic tendonitis or tendinopathy, patellar tendonitis, ligament sprains, and ligament laxity. The best treatment depends on what is causing the pain, how advanced the injury is, and whether the joint still has enough healthy structure to respond.

Why Image-Guided Knee Injections Matter

Accuracy is an important part of regenerative knee care. At Oregon Regenerative Medicine, knee procedures are performed using ultrasound imaging or fluoroscopic C-arm guidance. This allows the physician to see the joint and surrounding tissues in real time, place the injection precisely, and target the area of cartilage loss, joint fluid, ligament injury, or tissue damage.

Am I a Candidate for Knee Pain Treatment Without Surgery?

Before recommending treatment, our doctors will review your knee X-rays or MRI and perform a comprehensive exam and ultrasound imaging to pinpoint your pathology and better understand your symptoms, activity level, and goals. Some patients may be good candidates for regenerative therapy, while others may need a different type of care. If knee pain is limiting your life, a non-surgical evaluation can help you understand your options before considering knee replacement, arthroscopic surgery, steroid injections, or long-term pain medication.